Date(s):
Lundi 18 octobre 2021 - Mercredi 20 octobre 2021
Lieu(x):
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Le Professeur Jean-Louis Guéant, directeur du Laboratoire NGERE (Pôle BMS), organise avec la FASEB et le soutien de Lorraine Université d'Excellence une Autumn School 100% en ligne et en anglais, qui se tiendra du 18 au 20 octobre :
The Epigenome in Human Health and Diseases Conference
Agenda
Monday, October 18, 2021
| US Eastern Daylight Time (EDT) / Central European Summer Time (CEST) | Event |
|
8:30 am – 8:45 am (EDT) / |
Opening Remarks Pierre Mutzenhardt, President of the University of Lorraine, France |
| 8:45 am – 9:00 am (EDT) / 2:45 pm – 3:00 pm (CEST) |
Introduction of the Autumn School Jean-Louis Guéant, University of Lorraine, France |
| Day 1 Topic: Basics Aspects | |
| 9:00 am – 12:00 pm (EDT) / 3:00 pm – 6:00 pm (CEST) |
Morning Session Session Chair: Germano Cecere (Institut Pasteur, France) |
| 9:00 am – 10:00 am (EDT) / 3:00 pm – 4:00 pm |
John Edwards (Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA) “DNA Methylation and DNA Methyltransferases” (45 min presentation, 10 min Q&A, 5 min break) |
| 10:00 am – 11:00 pm (EDT) / 4:00 pm – 5:00 pm |
Jordana Bell (King's College London, UK) “Genetic Impacts on DNA Methylation” (45 min presentation, 10 min Q&A, 5 min break) |
| 11:00 am – 12:00 pm (EDT) / 5:00 pm – 6:00 pm |
Eric Verdin (Buck Institute for Research on Aging, Novato, CA, USA) “Chromatin Regulation and Intermediary Metabolism” (45 min presentation, 10 min Q&A, 5 min break) |
| 12:00 pm – 1:00 pm (EDT) / 6:00 pm – 7:00 pm (CEST) |
Lunch Break |
| 1:00 pm – 2:00 pm (EDT) / 7:00 pm – 8:00 pm (CEST) |
Poster Session Poster Presenters with last name beginning with A-L will need to stay in their Poster Chat Room to answer questions from attendees |
| 2:00 pm – 4:00 pm (EDT) / 8:00 pm – 10:00 pm (CEST) |
Afternoon Session Session Chair: Guillermo Barreto (University of Lorraine, France) |
| 2:00 pm – 3:00 pm (EDT) / 8:00 pm – 9:00 pm |
Jean-Yves Roignant (Faculté de Biologie et de Médecine, Université de Lausanne, Switzerland) “RNA Methylation” (45 min presentation, 10 min Q&A, 5 min break) |
| 3:00 pm – 4:00 pm (EDT) / 9:00 pm – 10:00 pm |
Germano Cecere (Institut Pasteur, France) “RNA Mechanisms of Epigenetic Inheritance” (45 min presentation, 10 min Q&A, 5 min break) |
| 4:00 pm – 4:30 pm (EDT) / 10:00 pm – 10:30 pm (CEST) |
Break |
| 4:30 pm – 5:30 pm (EDT) / 10:30 pm – 11:30 pm (CEST) |
Round table with the speakers of the day - Presentation and discussion of selected projects related to the topics of the day Session Co-Chairs: Jordana Bell (King's College London, UK) and Jonathan Turner (Luxembourg Institute of Health, Luxembourg) Xiaopu Zhang (King’s College, London) "Identification of Genetic Impacts on Human DNA Methylation Variability" (12 min presentation, 8 min discussion) Pauline Mosca (University of Lorraine, France) "Vitamin B 12 Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions" (12 min presentation, 8 min discussion) Hong Nhung Vu (Université de Iceland, Iceland) "Functional Role of PRDM7 in Melanoma and Its Regulation by MITF" (12 min presentation, 8 min discussion) |
Tuesday, October 19, 2021
| US Eastern Daylight Time (EDT) / Central European Summer Time (CEST) | Event |
| Day 2 Topic: The epigenome and environmental exposure in populations | |
| 9:00 am – 12:00 pm (EDT) / 3:00 pm – 6:00 pm (CEST) |
Morning Session Session Chair: Janine Felix (Erasmus MC, Department of Pediatrics, Rotterdam, The Netherlands) |
| 9:00 am – 10:00 am (EDT) / 3:00 pm – 4:00 pm (CEST) |
Abderrahim Oussalah (Inserm UMRS 1256 N-GERE, Nutrition-Genetics-Environmental Risks, University of Lorraine, France) “Bioinformatics Approaches in EWAS” (45 min presentation, 10 min Q&A, 5 min break) |
| 10:00 am – 11:00 pm (EDT) / 4:00 pm – 5:00 pm (CEST) |
Guillaume Bourque (McGill University & Genome Quebec Innovation Center, Montreal, Canada) “Data Repository-based Approaches in Comparative and Functional Epigenomics” (45 min presentation, 10 min Q&A, 5 min break) |
| 11:00 am – 11:30 pm (EDT) / 5:00 pm – 5:30 pm (CEST) |
Patrick Anglard (CNRS and University of Strasbourg, France) "Epigenetic Regulation of Circadian Clocks and Its Involvement in Drug Addiction" (25 min presentation, 5 min Q&A) |
| 11:30 am – 12:00 pm (EDT) / 5:30 pm – 6:00 pm (CEST) |
Jonathan Turner (Luxembourg Institute of Health, Luxembourg) "Moving Away from 5-methyl-Cytosine: The Role of 6mA in Our Adaptation to the Early Life Environment" (25 min presentation, 5 min Q&A) |
| 12:00 pm – 1:00 pm (EDT) / 6:00 pm – 7:00 pm (CEST) |
Lunch Break |
| 1:00 pm – 2:00 pm (EDT) / 7:00 pm – 8:00 pm (CEST) |
Poster Session Poster Presenters with last name beginning with M-Z will need to stay in their Poster Chat Room to answer questions from attendees |
| 2:00 pm – 4:00 pm (EDT) / 8:00 pm – 10:00 pm (CEST) |
Afternoon Session Session Chair: Guillaume Bourque (McGill University & Genome Quebec Innovation Center, Montreal, Canada) |
| 2:00 pm – 3:00 pm (EDT) / 8:00 pm – 9:00 pm (CEST) |
Janine Felix (Erasmus MC, Department of Pediatrics, Rotterdam, The Netherlands) “Pregnancy Exposures, Offspring DNA Methylation and Later-Life Health” (45 min presentation, 10 min Q&A, 5 min break) |
| 3:00 pm – 4:00 pm (EDT) / 9:00 pm – 10:00 pm (CEST) |
Philippa Melamed (Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel) “Epigenetic Mechanisms Regulating Reproduction and the Early-Life Environment” (45 min presentation, 10 min Q&A, 5 min break) |
| 4:00 pm – 4:30 pm (EDT) / 10:00 pm – 10:30 pm (CEST) |
Break |
| 4:30 pm – 5:30 pm (EDT) / 10:30 pm – 11:30 pm (CEST) |
Round table with the speakers of the day - Presentation and discussion of selected projects related to the topics of the day Session Co-Chairs: Abderrahim Oussalah (University of Lorraine, France), David Meyre (University of Lorraine, France) Cyrielle Holucka (Luxembourg Institute of Health, Luxembourg) "Early Life Adversity Accelerates the Aging Process" (12 min presentation, 8 min discussion) Youssef Siblini (NGERE, University of Lorraine, France) "Ionizing Radiations Induce Shared Epigenomic Signatures Unraveling Adaptive Mechanisms of Cancerous Cell Lines With or Without Methionine-Dependency" (12 min presentation, 8 min discussion) Alexandre Pelletier (Université de Lille, France) "Excessive Fetal Growth Affects HSC Homeostasis through Epigenetic Programming of the EGR1 Associated Transcriptional Network" (12 min presentation, 8 min discussion) |
Wednesday, October 20, 2021
| US Eastern Daylight Time (EDT) / Central European Summer Time (CEST) | Event |
| Day 3 Topic: Epigenome and Diseases | |
| 9:00 am – 12:00 pm (EDT) / 3:00 pm – 6:00 pm (CEST) |
Morning Session Session Chair: Struan Grant (Center for Spatial and Functional Genomics, Divisions of Human Genetics and Endocrinology & Diabetes, Children’s Hospital of Philadelphia, PA, USA) |
| 9:00 am – 10:00 am (EDT) / 3:00 pm – 4:00 pm (CEST) |
Struan Grant (Center for Spatial and Functional Genomics, Divisions of Human Genetics and Endocrinology & Diabetes, Children’s Hospital of Philadelphia, PA, USA) “Epigenome and Obesity-related Diseases” (45 min presentation, 10 min Q&A, 5 min break) |
| 10:00 am – 11:00 pm (EDT) / 4:00 pm – 5:00 pm (CEST) |
Manel Esteller (Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona, Spain) "Epigenome in Cancer" (45 min presentation, 10 min Q&A, 5 min break) |
| 11:00 am – 12:00 pm (EDT) / 5:00 pm – 6:00 pm (CEST) |
Esteban Ballestar (Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Badalona, Barcelona, Spain) "Epigenetics in Immune Diseases and Disorders" (45 min presentation, 10 min Q&A, 5 min break) |
| 12:00 pm – 1:00 pm (EDT) / 6:00 pm – 7:00 pm (CEST) |
Lunch Break |
| 1:00 pm – 2:00 pm (EDT) / 7:00 pm – 8:00 pm (CEST) |
Poster Session Free Discussion |
| 2:00 pm – 4:00 pm (EDT) / 8:00 pm – 10:00 pm (CEST) |
Afternoon Session Session Chair: Jean-Louis Guéant (University of Lorraine, France) |
| 2:00 pm – 2:30 pm (EDT) / 8:00 pm – 8:30 pm (CEST) |
Rosa-Maria Guéant-Rodriguez (Inserm UMRS 1256 N-GERE (Nutrition-Genetics-Environmental Risks), University of Lorraine, France) "The Epigenome in Cardiovascular Diseases" (25 min presentation, 5 min Q&A) |
| 2:30 pm – 3:00 pm (EDT) / 8:30 pm – 9:00 pm (CEST) |
Guillermo Barreto (University of Lorraine, France) "Epigenetic Regulation of Transcription and Spatial Genome Organization during Chronic Lung Diseases" (25 min presentation, 5 min Q&A) |
| 3:00 pm – 4:00 pm (EDT) / 9:00 pm – 10:00 pm (CEST) |
Jean-Louis Guéant (Inserm UMRS 1256 N-GERE (Nutrition-Genetics-Environmental Risks), University of Lorraine, France) “Epigenome and Rare Diseases” (45 min presentation, 10 min Q&A, 5 min break) |
| 4:00 pm – 4:30 pm (EDT) / 10:00 pm - 10:30 pm (CEST) |
Break |
| 4:30 pm – 5:30 pm (EDT) / 10:30 pm - 11:30 pm (CEST) |
Round table with the speakers of the day - Presentation and discussion of selected projects related to the topics of the day Session Co-Chairs: Struan Grant (Children’s Hospital of Philadelphia, PA, USA) and Esteban Ballestar (Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona) María Silvia Román Azcona (Albert-Ludwigs Universität Freiburg, Germany) "Epigenome Editing Enables PD1 Silencing in Primary T-cells" (12 min presentation, 8 min discussion) Sofia Raquel Fernandes Salta (Université de Porto, Portugal) "Triage of hr-HPV Positive Women Enrolled in Cervical Cancer Screening Program: DNA Methylation Markers as Potential Tool" (12 min presentation, 8 min discussion) Ramia Safar (NGERE, University of Lorraine, France) "Epigenome Alterations in Food Allergy: A Systematic Review of Candidate Gene and Epigenome-Wide Association Studies" (12 min presentation, 8 min discussion) |
| 5:30 pm – 6:00 pm (EDT) / 11:30 pm - 12:00 am (CEST) |
Concluding Discussion |
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