FASEB Autumn School : The Epigenome in Human Health and Diseases Conference (LUE)

2:45 pm – 3:00 pm (CEST)

3:00 pm – 6:00 pm (CEST)

Session Chair: Germano Cecere (Institut Pasteur, France)

3:00 pm – 4:00 pm

“DNA Methylation and DNA Methyltransferases” (45 min presentation, 10 min Q&A, 5 min break)

4:00 pm – 5:00 pm

“Genetic Impacts on DNA Methylation” (45 min presentation, 10 min Q&A, 5 min break)

5:00 pm – 6:00 pm

“Chromatin Regulation and Intermediary Metabolism” (45 min presentation, 10 min Q&A, 5 min break)

Poster Presenters with last name beginning with A-L will need to stay in their Poster Chat Room to answer questions from attendees

8:00 pm – 9:00 pm

“RNA Methylation” (45 min presentation, 10 min Q&A, 5 min break)

9:00 pm – 10:00 pm

“RNA Mechanisms of Epigenetic Inheritance” (45 min presentation, 10 min Q&A, 5 min break)

Session Co-Chairs: Jordana Bell (King’s College London, UK) and Jonathan Turner (Luxembourg Institute of Health, Luxembourg)

Xiaopu Zhang (King’s College, London)

« Identification of Genetic Impacts on Human DNA Methylation Variability » (12 min presentation, 8 min discussion)

Pauline Mosca (University of Lorraine, France)

« Vitamin B 12 Deficiency Dysregulates m6A mRNA Methylation of Genes Involved in Neurological Functions » (12 min presentation, 8 min discussion)

Hong Nhung Vu (Université de Iceland, Iceland)

« Functional Role of PRDM7 in Melanoma and Its Regulation by MITF » (12 min presentation, 8 min discussion)

3:00 pm – 6:00 pm (CEST)

Session Chair: Janine Felix (Erasmus MC, Department of Pediatrics, Rotterdam, The Netherlands)

3:00 pm – 4:00 pm (CEST)

“Bioinformatics Approaches in EWAS” (45 min presentation, 10 min Q&A, 5 min break)

4:00 pm – 5:00 pm (CEST)

“Data Repository-based Approaches in Comparative and Functional Epigenomics” (45 min presentation, 10 min Q&A, 5 min break)

5:00 pm – 5:30 pm (CEST)

5:30 pm – 6:00 pm (CEST)

Poster Presenters with last name beginning with M-Z will need to stay in their Poster Chat Room to answer questions from attendees

8:00 pm – 9:00 pm (CEST)

“Pregnancy Exposures, Offspring DNA Methylation and Later-Life Health” (45 min presentation, 10 min Q&A, 5 min break)

9:00 pm – 10:00 pm (CEST)

“Epigenetic Mechanisms Regulating Reproduction and the Early-Life Environment” (45 min presentation, 10 min Q&A, 5 min break)

Session Co-Chairs: Abderrahim Oussalah (University of Lorraine, France), David Meyre (University of Lorraine, France)

Cyrielle Holucka (Luxembourg Institute of Health, Luxembourg)

« Early Life Adversity Accelerates the Aging Process » (12 min presentation, 8 min discussion)

Youssef Siblini (NGERE, University of Lorraine, France)

« Ionizing Radiations Induce Shared Epigenomic Signatures Unraveling Adaptive Mechanisms of Cancerous Cell Lines With or Without Methionine-Dependency » (12 min presentation, 8 min discussion)

Alexandre Pelletier (Université de Lille, France)

« Excessive Fetal Growth Affects HSC Homeostasis through Epigenetic Programming of the EGR1 Associated Transcriptional Network » (12 min presentation, 8 min discussion)

3:00 pm – 6:00 pm (CEST)

Session Chair: Struan Grant (Center for Spatial and Functional Genomics, Divisions of Human Genetics and Endocrinology & Diabetes, Children’s Hospital of Philadelphia, PA, USA)

3:00 pm – 4:00 pm (CEST)

“Epigenome and Obesity-related Diseases” (45 min presentation, 10 min Q&A, 5 min break)

4:00 pm – 5:00 pm (CEST)

« Epigenome in Cancer » (45 min presentation, 10 min Q&A, 5 min break)

5:00 pm – 6:00 pm (CEST)

« Epigenetics in Immune Diseases and Disorders » (45 min presentation, 10 min Q&A, 5 min break)

Free Discussion

Session Chair: Jean-Louis Guéant (University of Lorraine, France)

8:00 pm – 8:30 pm (CEST)

8:30 pm – 9:00 pm (CEST)

9:00 pm – 10:00 pm (CEST)

“Epigenome and Rare Diseases” (45 min presentation, 10 min Q&A, 5 min break)

Session Co-Chairs: Struan Grant (Children’s Hospital of Philadelphia, PA, USA) and Esteban Ballestar (Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona)

María Silvia Román Azcona (Albert-Ludwigs Universität Freiburg, Germany)

« Epigenome Editing Enables PD1 Silencing in Primary T-cells » (12 min presentation, 8 min discussion)

Sofia Raquel Fernandes Salta (Université de Porto, Portugal)

« Triage of hr-HPV Positive Women Enrolled in Cervical Cancer Screening Program: DNA Methylation Markers as Potential Tool » (12 min presentation, 8 min discussion)

Ramia Safar (NGERE, University of Lorraine, France)

« Epigenome Alterations in Food Allergy: A Systematic Review of Candidate Gene and Epigenome-Wide Association Studies » (12 min presentation, 8 min discussion)